Bone mineral density during long-term prophylaxis with heparin in pregnancy
作者： Thomas C. Dahlman , Hans E. Sjöberg , Hans Ringertz
DOI: 10.1016/S0002-9378(94)70149-0
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摘要: OBJECTIVE: We studied the effect of long-term heparin treatment on bone mass during pregnancy. STUDY DESIGN: Thromboprophylaxis with was given to 39 women pregnancy for a mean 28 weeks and an average 6 post partum. Bone mineral density measured single-photon absorptiometry distal ultradistal parts forearm determined at time start (mean, twelfth week gestation), immediately partum, 7 The dosage 17,300 IU/day. A control group 34 normal pregnant comparison. RESULTS: In treated heparin, there almost 5% reduction in trabecular ( p CONCLUSION: Long-term is associated loss, but indications reversible changes are observed.
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