Improvement of the chemical and physical stability of the EC1 domain of E -cadherin by blocking its disulfide-mediated dimerization

Jörg Klingelhöfer, Oscar Y. Laur, Regina B. Troyanovsky, Sergey M. Troyanovsky, Dynamic interplay between adhesive and lateral E-cadherin dimers Molecular and Cellular Biology. ,vol. 22, pp. 7449- 7458 ,(2002) , 10.1128/MCB.22.21.7449-7458.2002

A. Sorina Morar, Mark D. Chavez, Jeffrey L. Schrimsher, PEGylation of proteins : A structural approach Biopharm International. ,vol. 19, ,(2006)

Daniel H Doherty, George N Cox, Alison M Bendele, Mary S Rosendahl, Darin J Smith, Site-Specific Protein PEGylation: Application to Cysteine Analogs of Recombinant Human Granulocyte Colony-Stimulating Factor. BioProcess international. ,vol. 3, pp. 52- 60 ,(2005)

Jay A. Schrier, Richard A. Kenley, Rick Williams, Robert J. Corcoran, Yangkil Kim, Richard P. Northey, Jr, Darren D'Augusta, Michael Huberty, Degradation Pathways for Recombinant Human Macrophage Colony-Stimulating Factor in Aqueous Solution Pharmaceutical Research. ,vol. 10, pp. 933- 944 ,(1993) , 10.1023/A:1018990001310

Ernawati Sinaga, Seetharama DS Jois, Mike Avery, Irwan T Makagiansar, Usman SF Tambunan, Kenneth L Audus, Teruna J Siahaan, None, Increasing paracellular porosity by E-cadherin peptides: discovery of bulge and groove regions in the EC1-domain of E-cadherin. Pharmaceutical Research. ,vol. 19, pp. 1170- 1179 ,(2002) , 10.1023/A:1019850226631

Irwan T. Makagiansar, Mike Avery, Yongbo Hu, Kenneth L. Audus, Teruna J. Siahaan, Improving the selectivity of HAV-peptides in modulating E-cadherin-E-cadherin interactions in the intercellular junction of MDCK cell monolayers. Pharmaceutical Research. ,vol. 18, pp. 446- 453 ,(2001) , 10.1023/A:1011094025008

Cecilia Oliyai, Ronald T. Borchardt, Chemical Pathways of Peptide Degradation. IV. Pathways, Kinetics, and Mechanism of Degradation of an Aspartyl Residue in a Model Hexapeptide Pharmaceutical Research. ,vol. 10, pp. 95- 102 ,(1993) , 10.1023/A:1018981231468

Sophie Vanwetswinkel, Stephane Plaisance, Zhang Zhi-yong, Ingrid Vanlinthout, Kathleen Brepoels, Ignace Lasters, Désiré Collen, Laurent Jespers, Pharmacokinetic and thrombolytic properties of cysteine-linked polyethylene glycol derivatives of staphylokinase. Blood. ,vol. 95, pp. 936- 942 ,(2000) , 10.1182/BLOOD.V95.3.936.003K20_936_942

Akinao Nose, Katsumi Tsuji, Masatoshi Takeichi, Localization of specificity determining sites in cadherin cell adhesion molecules Cell. ,vol. 61, pp. 147- 155 ,(1990) , 10.1016/0092-8674(90)90222-Z

Irwan T. Makagiansar, Phuong D. Nguyen, Atsutoshi Ikesue, Krzysztof Kuczera, William Dentler, Jeffrey L. Urbauer, Nadezhda Galeva, Michail Alterman, Teruna J. Siahaan, Disulfide Bond Formation Promotes the cis- and trans-Dimerization of the E-cadherin-derived First Repeat Journal of Biological Chemistry. ,vol. 277, pp. 16002- 16010 ,(2002) , 10.1074/JBC.M200916200