Spatial Resolution and the Magnitude of Infarct Volume Measurement Error in DWI in Acute Ischemic Stroke.

摘要: BACKGROUND AND PURPOSE: Infarct volume in acute ischemic stroke is an important prognostic marker and determines endovascular treatment decisions. This study evaluates the magnitude potential clinical impact of error related to partial effects infarct measurement on diffusion-weighted MR imaging explores how increasing spatial resolution could reduce this error. MATERIALS METHODS: Diffusion-weighted 393 patients with stroke, whom 56 had anterior circulation large-vessel occlusion, was coregistered standard space. Lesion boundaries were manually segmented. A 3D lesion-volume model resampled for voxel sizes from 4 × 8 1 2 mm, surface-volume, corresponding error, calculated. The number cases which therapy core threshold 70 mL contained within margin calculated as a function resolution. RESULTS: mean 27.2 ± 49.9 mL. surface 14.7 20.8 mL mm 7.4 10.7 mL With 7/56 (12.5%) while size, 3/56 (5%). range potentially misclassified lesions dropped 46.5–94.1 mL 64.4–80.1 mL CONCLUSIONS: Partial effect source stroke. Increasing substantially decreases Standard use high-resolution DWI should be considered increase reliability measurements.