Antibiotic resistance profiles of coagulase-negative staphylococci in livestock environments.

摘要: Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) have globally emerged in animal husbandry. In addition to methicillin resistance, LA-MRSA may carry a variety of novel and uncommon antimicrobial resistance genes. Occurrence the same genes coagulase-negative staphylococci (CoNS) S. suggests an ongoing genetic exchange between other whose driving forces ecological niche farm environment are, however, still poorly understood. To assess potential CoNS as putative reservoirs for antibiotic genes, we analysed susceptibility from dust manure samples obtained 41 pig farms Germany, most them (36 41) with proven LA-MRSA/MSSA history. Among 344 isolates analysed, 18 different species were identified sciuri represented prevalent (46%). High rates detected tetracycline (71%), penicillin (65%) oxacillin (64%) well fusidic acid (50%), which was mainly due reduced among isolates. exhibited pronounced multiresistance, many characterised by carriage number (multi)resistance (e.g. cfr, apmA, fexA) decreased towards last resort antibiotics such linezolid daptomycin. The combined data suggest that harbours significant gene pool requires further attention. We hypothesise members this species, their flexible lifestyle, might contribute spread livestock environments.