11 – Mechanisms of DNA Excision Repair in Human Cells

作者: B. STRAUSS , K. TATSUMI , P. KARRAN , N.P. HIGGINS , E. BEN-ASHER

DOI: 10.1016/B978-0-12-279202-1.50018-X

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摘要: It is possible to distinguish three separate pathways for the metabolism of DNA: replication, recombination, and repair. This distinction not absolute and, as demonstrated below, there are large regions overlap. In this paper we would like concentrate on process(es) DNA repair consider question their general biological role. There two different excision pathways; nucleotide pathway, base (apurinic) Our evidence suggests that bulk induced by polycyclic aromatic hydrocarbons (PAH's) in human cells comes via pathway.

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