Neue Synthese von 4-Azaphenothiazin
作者： Bernhard Kutscher , Hans Reinhold Dieter , Hans-Günther Trömer , Beate Bartz , Jürgen Engel
DOI: 10.1002/JLAC.199519950381
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摘要: New Synthesis of 4-Azaphenothiazine1 The reaction 2-chloropyridine with 2-aminothiophenol gives N-(2-mercaptophenyl)-2-pyridinamine (2) which is cyclised to give 4-azaphenothiazine (3), a useful intermediate for pharmaceuticals. An improved one-pot synthesis reported and mechanism proposed.
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