MIB-1 immunoreactivity reveals different labelling in low-grade and in malignant epithelial neoplasms of the choroid plexus.

摘要: MIB-1 immunohistochemistry was carried out on a retrospective biopsy series of epithelial choroid plexus neoplasms in order to assess the proliferation rate tumour cells. The material included 14 cases papilloma (WHO grade I) and five carcinoma III). There one recurrent group, while three patients with experienced recurrence. Choroid obtained at autopsy from paediatric adult unrelated diseases served as control. average labelling index papillomas 3.7%, that carcinomas 14%, normal 0.02% 0.06%. age sex well localization were not found influence reactivity. lesions significantly different corresponding primary tumours. High indices associated less favourable post-operative outcome atypical histology. However, most tumours histological features did exhibit distinctive indices. Analysis growth fraction by may prove useful ancillary method for assessing malignant potential neoplasms.