A thiol-responsive and self-immolative podophyllotoxin prodrug for cancer therapy
作者： Meili Hou , Zhigang Xu , Baosheng Li , Yi Lu , Shanshan Li
DOI: 10.1016/J.TETLET.2021.153044
关键词:
摘要: … Thiol content tests were used to detect the GSH depletion in CT26 cells. CT26 cells were … In summary, by conjugating the anticancer drug PPT with benzopyran derivative, a novel …
sci-hub.st 参考文章(61)
Bhaskar S. Mandavilli, Michael S. Janes, Detection of Intracellular Glutathione Using ThiolTracker Violet Stain and Fluorescence Microscopy Current protocols in immunology. ,vol. 53, ,(2010) , 10.1002/0471142956.CY0935S53
Yoshikazu Ikuta, Yoshitaka Koseki, Tsunenobu Onodera, Hidetoshi Oikawa, Hitoshi Kasai, The effect of molecular structure on the anticancer drug release rate from prodrug nanoparticles Chemical Communications. ,vol. 51, pp. 12835- 12838 ,(2015) , 10.1039/C5CC04164C
Stefan Bräse, Carmen Gil, Kerstin Knepper, Viktor Zimmermann, Organic Azides: An Exploding Diversity of a Unique Class of Compounds Angewandte Chemie. ,vol. 44, pp. 5188- 5240 ,(2005) , 10.1002/ANIE.200400657
Salwa K Poole, Colin F Poole, Separation methods for estimating octanol-water partition coefficients. Journal of Chromatography B. ,vol. 797, pp. 3- 19 ,(2003) , 10.1016/J.JCHROMB.2003.08.032
Ho Yong Lee, Xuan Jiang, Dongwhan Lee, Kinetics of self-immolation: faster signal relay over a longer linear distance? Organic Letters. ,vol. 11, pp. 2065- 2068 ,(2009) , 10.1021/OL900433G
Rubi Mahato, Wanyi Tai, Kun Cheng, Prodrugs for Improving Tumor Targetability and Efficiency Advanced Drug Delivery Reviews. ,vol. 63, pp. 659- 670 ,(2011) , 10.1016/J.ADDR.2011.02.002
Youqing Shen, Erlei Jin, Bo Zhang, Caitlin J. Murphy, Meihua Sui, Jian Zhao, Jinqiang Wang, Jianbin Tang, Maohong Fan, Edward Van Kirk, William J. Murdoch, Prodrugs forming high drug loading multifunctional nanocapsules for intracellular cancer drug delivery. Journal of the American Chemical Society. ,vol. 132, pp. 4259- 4265 ,(2010) , 10.1021/JA909475M
Xumeng Wu, Xuanrong Sun, Zhiqian Guo, Jianbin Tang, Youqing Shen, Tony D. James, He Tian, Weihong Zhu, In vivo and in situ tracking cancer chemotherapy by highly photostable NIR fluorescent theranostic prodrug. Journal of the American Chemical Society. ,vol. 136, pp. 3579- 3588 ,(2014) , 10.1021/JA412380J
Duvvuri Subrahmanyam, B. Renuka, C.V. Laxmana Rao, P.Sangeeta Sagar, Dhanvanthri S. Deevi, J.Moses Babu, K. Vyas, Novel D-ring analogues of podophyllotoxin as potent anti-cancer agents ☆ Bioorganic & Medicinal Chemistry Letters. ,vol. 8, pp. 1391- 1396 ,(1998) , 10.1016/S0960-894X(98)00232-7
Frédéric Friscourt, Christoph J. Fahrni, Geert-Jan Boons, A Fluorogenic Probe for the Catalyst-Free Detection of Azide-Tagged Molecules Journal of the American Chemical Society. ,vol. 134, pp. 18809- 18815 ,(2012) , 10.1021/JA309000S