Nanopore-based nucleic acid analysis with mixed fret detection

作者: Martin Huber , Bason E. Clancy , Paul Hardenbol

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摘要: Various methods, systems and devices for optical detection analysis of polymers, such as polynucleotides, using nanopores, e.g., determining sequences nucleic acids, are provided herein. In certain variations, methods a nucleotide sequence polynucleotide, which include measuring mixed FRET signals polynucleotide translocates through nanopore the from signals, provided.

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