作者: Alexander Riechers , Anja Katrin Bosserhoff , Burkhard König , Jennifer Schmidt
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摘要: The present invention relates to peptides and antibodies which bind melanoma inhibitory activity protein the uses of such antibodies. also nucleic acids coding for or pharmaceutical compositions comprising acids. small molecule compounds compounds. Moreover, a method preventing dimerization and/or aggregation (MIA) protein. is based on identification relevant sites interaction MIA with peptides/antibodies. Considering amino acid sequence this deprived from signalling peptide, residues involved in are selected from: A7, K53, G54, R55, R57, L58, F59, V64, Y69, R85, D87, K91, more preferably C17, S18, Y47, G61, G66, D67, L76, W102, D103, C106.