Role of Self-Loop in Cell-Cycle Network of Budding Yeast

作者: Shu-ichi Kinoshita , Hiroaki Yamada

DOI: 10.4236/OJBIPHY.2019.91002

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摘要: Study of network dynamics is very active area in biological and social sciences. However, the relationship between structure attractors has not been fully understood yet. In this study, we numerically investigated role degenerate self-loops on its basin size using budding yeast cell-cycle model. network, all negatively suppress node (self-inhibition loops) are only fixed points, i.e. point attractors. It found that there a simple division rule state space by removing when consist The attractor with largest robust against change self-inhibition loop. Furthermore, some limit cycles period 2 appear as new self-activation loop added to original network. also shown even case, robust.

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