Direct defluorinative amidation-hydrolysis reaction of gem-difluoroalkenes with N,N-dimethylformamide, and primary and secondary amines.

作者: Biyun Wang , Xianghu Zhao , Qingyun Liu , Song Cao

DOI: 10.1039/C8OB02322K

关键词:

摘要: A novel and efficient method for the synthesis of arylacetamides by reactions gem-difluoroalkenes with N,N-dialkylformamides, primary secondary amines assistance KOtBu water was developed.

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