Seroprevalence of hepatitis E virus differs significantly among first and second generation migrant groups in Amsterdam, the Netherlands

摘要: s / Journal of Clinical Virology 70 (2015) S1–S126 S9 Methods: Pediatric inpatients (0–5 year) were identified between January 1st, 2013 and December 31st, 2014 for whom a respiratory TAC analysis was ordered within 24hours admission. Patients with symptoms, selected by All Patient Refined Diagnosis Related Group (APR-DRG). The panel (implemented January, 2013) included testing following 34 pathogens: influenza A virus (H1, H3, H7), B virus, RSV A, B, parainfluenza 1 to 4, adenovirus, rhinovirus, enterovirus, hMPV, coronavirus (229E, HKU1, OC43, NL63, MERS), bocavirus, cytomegalovirus, parechovirus, mumps measles Mycoplasma pneumoniae, Chlamydophila psittaci, Bordetella pertussis, parapertussis, holmesii/bronchiseptica, Coxiella burnetii, Legionella pneumophila, Pneumocystis jiroveccii, Aspergillus species. Results: During the study period, 875 pediatric patients admitted among who 298 (34.1%) diagnosed pathology received antibiotic therapy (180 in 2013, 118 2014). In 192 tests different episodes performed. Based on results this novel test, clinicians only prescribed antibiotics 63 (32.8%) reflecting possible reduction use 129 patients. One year after implementation, 164 infectious conducted, slight overconsumption linked introduction period. However, 69 (42%) led use. 95 (58%) did not evoke prescription. Conclusion: change clinical management based observed. Awareness potential viral pathogens causing LRTI’s resulted Implementation had benefits: early, highly sensitive specific adequate broad pathogen diagnosis, improved individual child, reduced selection resistant bacteria, considering coinfections, treatment adaptation options, transmission prevention opportunity, expanding view epidemiology, need further laboratory evaluation, possibly reducing overall costs care. conclusion, guides decision making reduces inadequate infections. http://dx.doi.org/10.1016/j.jcv.2015.07.028