Fentanyl transdermal system. Pain management at home.

摘要: Abstract PROBLEM BEING ADDRESSED: About 65% of patients with advanced malignancies experience cancer pain. Although oral opioids provide effective analgesia for most these patients, alternate routes drug delivery are often necessary as the disease progresses. PURPOSE OF PROGRAM: To study use Duragesic (fentanyl transdermal system), only opioid approved in Canada treating chronic pain adults. MAIN COMPONENTS: Transdermal fentanyl was prescribed a heterogeneous group 44 (aged 29 to 82 years) treat (37 patients), non-malignant (six and associated terminal AIDS (one patient), periods 2 384 days. Patients were treated individually switched from other when no longer possible. Doses titrated ranged 25 micrograms/h 300 micrograms/h. Incidental effectively short-acting opioids. CONCLUSIONS: Eighty percent experienced good analgesia, which led an overall improvement their quality life. discontinued 17% due intractable nausea, diarrhea, adherence problems, or poor analgesia. Many wore system until they died few days before death severe increasing necessitated parenteral The side effects similar those conventional Patient compliance acceptance this noninvasive, continuous has been excellent; its simplicity administration allows be cared at home.