作者: H. H. Hartgrink , H. Putter , E. Klein Kranenbarg , J. J. Bonenkamp , C. J. H. van de Velde
DOI: 10.1046/J.1365-2168.2002.02220.X
关键词:
摘要: Background: Western patients with gastric cancer often present incurable disease. The role of palliative surgical resection is still debatable. Non-curatively treated from the Dutch Gastric Cancer Trial were studied to define more accurately which might benefit resection. Methods: In 285 (26 per cent) randomized found have tumours at laparotomy. Four signs incurability noted: irresectable tumour (T+), hepatic metastasis (H+), peritoneal (P+) and distant lymph node (N4+). Patients had either an explorative laparotomy, a gastroenterostomy, or (partial total). In analysis, particular attention was paid prognostic factors age, number metastatic features, combination these. Results: Overall survival time greater if performed (8·1 versus 5·4 months; P < 0·001). For aged over 70 years there advantage about 3 months carried out. Morbidity perioperative mortality rates in this older age group were, however, high (50 20 cent respectively). one site significant (survival 10·5 6·7 = 0·034). two sites no (5·7 4·6 0·084). Combination these indicates that less than will significantly resection, contrast other combinations factors. Conclusion: Age as well should be taken into account when considered. Palliative may beneficial for under load restricted site. © 2002 British Journal Surgery Society Ltd