Mechanisms of Electrogenic Sodium Transport in the Amphibian Colon
作者： Rolf Krattenmacher , Wolfgang Clauss
DOI: 10.1007/978-3-642-77118-7_2
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摘要: In the early 1950s Ussing and Zerahn (1951) introduced technology of short-circuit current as a method to study active ion transport through isolated epithelia. They could show that electrical potential difference across frog skin is caused by primary absorption mechanism for sodium ions, located in tissue itself. Since time this well amphibian tissues became more established many “epithelial laboratories” all over world. meantime hundreds if not thousands investigations dealing with system have been published, wereby toad urinary bladder developed into classical model systems. contrast, processes intestine, especially those large intestine (colon), only relatively poorly investigated.
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