作者: Walter H. Chang , Kyle T. Chang , Jimmy Li
DOI: 10.1007/978-3-662-06079-7_6
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摘要: Biological studies suggest that extremely low frequency-electromagnetic fields (ELF-EMF) operate by modulating normal control mechanisms available to the cell. There is an abundance of experimental and clinical data which indicate exposure exogenous electromagnetic surprisingly levels can have a profound effect on large variety biological systems, including abovementioned bone disorders such as fracture osteoporosis. The obtained from in vitro systems current activity cell (e.g., division or differentiation) be modulated. As number experiments EMF effects increases it becoming increasingly evident, will shown below, more cursory consideration must given. Many employ transformed rather than cells. One question whether cells are abnormal represent best model for elucidating interaction mechanisms. A better approach might use simpler, well-studied yeast bacteria. obvious advantage employing these organisms elucidate transduction pathway(s) they well characterized and, importantly, endless array mutants investigator. Historically, has proved essential tool elucidation cellular pathways. approved therapeutic weak result devices were designed modulate (not initiate) tissue growth repair. It quite clear all dosimetry amount energy deposited target negligible compared required affected biochemical pathway. Thus, capability bioeffect appears reside informational content waveform. This may provide part explanation sensitivity living magnetic fields. Finally, site(s) between ELF-EMF remain elaborated. Although there numerous hypotheses membrane represents primary site interaction, also several different showing cell-free responsive EMF. debate about potential hazards value continue until mechanism been clarified. problem how perturb function understood when techniques molecular biology, genetics, biochemistry, biophysics directed together answer question.