Electrically stimulated sartorius neosphincter: Canine model of activation and skeletal muscle transformation

摘要: The sartorius muscle was transposed into the abdominal cavity of six dogs, passed around a Thiry-Vella loop and sutured to itself form neosphincter. activated by electrical stimulation on contraction neosphincter stopped or reduced flow saline through in all animals until onset fatigue. Continuous low frequency used transform skeletal muscle, when studied after mean 8 weeks (range 6-11 weeks) for significantly longer period time (P = 0.027). Associated with improved function significant decrease fusion 0.003) prolongation stimulus-peak tension as assessed strain gauge 0.002). changes properties suggest that continuous transformed fibres from type 2 1, resulting fatigue resistance potential sphincter activity.