作者: Morgan A. Brown , Leila Barker , Lewis Semprini , Ethan D. Minot
DOI: 10.1021/ACS.ESTLETT.5B00025
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摘要: Using a graphene field-effect transistor bio- sensor, we monitored the pH inside living biofilm with fast temporal resolution (∼1 s) over multihour time periods. The atomically thin sensor is positioned between and supporting silicon oxide surface, providing noninvasive access to conditions at base of biofilm. We determine transient changes in when metabolizes substrate molecules it exposed biocide. approximately 0.01 units using 1 s averaging. drift per hour. Our results demonstrate potential this technology study metabolism monitor health.