Postinjury Multiple Organ Failure
作者： Frederick A. Moore , Angela Sauaia , Ernest E. Moore , James B. Haenel , Jon M. Burch
DOI: 10.1097/00005373-199604000-00001
关键词:
摘要: To better define the epidemiology of postinjury multiple organ failure (MOF), we prospectively evaluated 457 high-risk trauma patients who survived more than 48 hours. Overall, 70 (15%) developed MOF. In 27 (39%) patients, occurrence was early, while in 43 (61%) presentation delayed. At presentation, early MOF had cardiac dysfunction, late greater hepatic failure. Indices shock were critical risk factors for MOF, advanced age important While and a similar high incidence major infections, these appeared to be precipitating Finally, mortality is similar, appear succumb faster. conclusion, remains significant challenge appears present at least two patterns (i.e., versus late). Better understanding relative roles dysfunctional inflammation infections may facilitate development new strategies prevention treatment morbid syndrome.
sci-hub.st 参考文章(49)
CHARLES J. FISHER, STEVEN M. OPAL, JEAN-FRANÇOIS DHAINAUT, SUE STEPHENS, JANICE L. ZIMMERMAN, PETER NIGHTINGALE, SIMON J. HARRIS, ROLAND M. H. SCHEIN, EDWARD A. PANACEK, JEAN-LOUIS VINCENT, GARRETT E. FOULKE, EDWARD L. WARREN, CHRIS GARRARD, GILBERT PARK, MARK W. BODMER, JONATHAN COHEN, CEES VAN DER LINDEN, ALAN S. CROSS, JERALD C. SADOFF, Influence of an anti-tumor necrosis factor monoclonal antibody on cytokine levels in patients with sepsis Critical Care Medicine. ,vol. 21, pp. 318- 327 ,(1993) , 10.1097/00003246-199303000-00006
Frederick A. Moore, Ernest E. Moore, Evolving Concepts in the Pathogenesis of Postinjury Multiple Organ Failure Surgical Clinics of North America. ,vol. 75, pp. 257- 277 ,(1995) , 10.1016/S0039-6109(16)46587-4
R. I. C. Wesdorp, M. A. Cuesta, J. J. P. Nauta, D. D. Tran, P. A. M. Van Leeuwen, Risk factors for multiple organ system failure and death in critically injured patients. Surgery. ,vol. 114, pp. 21- 30 ,(1993)
HENDRICK K. F. VAN SAENE, CHRISTIAAN C. STOUTENBEEK, JAMES K. STOLLER, Selective decontamination of the digestive tract in the intensive care unit: current status and future prospects. Critical Care Medicine. ,vol. 20, pp. 691- 703 ,(1992) , 10.1097/00003246-199205000-00024
WENDELL A. GOINS, H. NEAL REYNOLDS, DAVID NYANJOM, C. MICHAEL DUNHAM, Outcome following prolonged intensive care unit stay in multiple trauma patients. Critical Care Medicine. ,vol. 19, pp. 339- 345 ,(1991) , 10.1097/00003246-199103000-00010
E. FAIST, A. MEWES, C. C. BAKER, TH. STRASSER, S. S. ALKAN, P. RIEBER, G. HEBERER, Prostaglandin E2 (PGE2)-dependent suppression of interleukin alpha (IL-2) production in patients with major trauma. Journal of Trauma-injury Infection and Critical Care. ,vol. 27, pp. 837- 848 ,(1987) , 10.1097/00005373-198708000-00001
Donald E. Fry, Multiple System Organ Failure: The Role of Uncontrolled Infection Archives of Surgery. ,vol. 115, pp. 136- 140 ,(1980) , 10.1001/ARCHSURG.1980.01380020006003
Angela Sauaia, Frederick A. Moore, Ernest E. Moore, James B. Haenel, Linda Kaneer, Robert A. Read, Diagnosing pneumonia in mechanically ventilated trauma patients: endotracheal aspirate versus bronchoalveolar lavage. Journal of Trauma-injury Infection and Critical Care. ,vol. 35, pp. 512- 517 ,(1993) , 10.1097/00005373-199310000-00003
David G. Ashbaugh, Idiopathic Pulmonary Fibrosis in Adult Respiratory Distress Syndrome Archives of Surgery. ,vol. 120, pp. 530- 535 ,(1985) , 10.1001/ARCHSURG.1985.01390290012002
Abraham J. Botha, Frederick A. Moore, Ernest E. Moore, Angela Sauaia, Anirban Banerjee, Verlyn M. Peterson, Early neutrophil sequestration after injury: a pathogenic mechanism for multiple organ failure. Journal of Trauma-injury Infection and Critical Care. ,vol. 39, pp. 411- 417 ,(1995) , 10.1097/00005373-199509000-00003