Highly sensitive biomarker panels
作者： Philippe J. Goix , Robert Puskas , Douglas Held , Sara Le , John Todd
DOI:
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摘要: Cardiovascular disease, e.g., congestive heart failure, is often first diagnosed after the onset of clinical symptoms, eliminating potential for early intervention. The invention provides a multi-marker immunoassay, including cardiac pathology and vascular inflammation biomarkers, yielding more sensitive assay detection CHF in plasma. A panel consisting (cTnI, BNP) (IL-6, TNFα, IL-17a) biomarkers provided sensitivity 94% association with CHF.
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