Inhibitory effects of flavonoids on xanthine oxidase.

摘要: The stems of Bougainvillea spectabillis Wild (Nyctaginaceae) have been used in folk medicine for hepatis, and spinasterol and quercetin were isolated and characterized from the plant leaves in this study. These constituents have not been previously isolated from Bougainvillea spectabillis W. Quercetin, the flavonoid, was found as active principle because it showed a strong activity on xanthine oxidase inhibition (IC50= 7.23 microM) in this study as well as in the literature. Since xanthine oxidase serum levels are increased in …