Low-Level Laser Therapy Induces Dose-Dependent Reduction of TNFα Levels in Acute Inflammation
作者： F Aimbire , Regiane Albertini , MTT Pacheco , Hugo Caire Castro-Faria-Neto , PSLM Leonardo
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摘要: Objective: The aim of this study was to investigate if low-level laser therapy (LLLT) can modulate acute inflammation and tumor necrosis factor (TNFα) levels. Background Data: Drug with TNFα-inhibitors has become standard treatment for rheumatoid arthritis, but it is unknown LLLT reduce or TNFα levels in inflammatory disorders. Methods: Two controlled animal studies were undertaken, 35 male Wistar rats randomly divided into five groups each. Rabbit antiserum ovalbumin instilled intrabronchially one the lobes, followed by intravenous injection 10 mg 0.5 mL induce lung injury. first served define time profile activity 4 h, while second compared three different doses a control group chlorpromazine at timepoint where increased. irradiated within 5 min site injury 650-nm Ga-Al-As laser. Results: There a...
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researchgate.net 参考文章(32)
Annmarie L. Dunican, Stephanie J. Leuenroth, Patricia Grutkoski, Alfred Ayala, Hank H. Simms, TNFα-INDUCED SUPPRESSION OF PMN APOPTOSIS IS MEDIATED THROUGH INTERLEUKIN-8 PRODUCTION Shock. ,vol. 14, pp. 284- 289 ,(2000) , 10.1097/00024382-200014030-00007
Jeffrey R Basford, Laser therapy: scientific basis and clinical role. Orthopedics. ,vol. 16, pp. 541- 547 ,(1993) , 10.3928/0147-7447-19930501-06
L Brosseau, V Welch, G Wells, R deBie, A Gam, K Harman, M Morin, B Shea, P Tugwell, Low level laser therapy (classes I, II and III) in the treatment of rheumatoid arthritis. Cochrane Database of Systematic Reviews. ,(2000) , 10.1002/14651858.CD002049
A Giuliani, L Calzà, P Monteforte, M Farinelli, L Giardino, R Capra, L Baratto, M Fernandez, G Rovetta, Very low level laser therapy attenuates edema and pain in experimental models. International Journal of Tissue Reactions-experimental and Clinical Aspects. ,vol. 26, pp. 29- 37 ,(2004)
Ara A. Vaporciyan, Michael S. Mulligan, Peter A. Ward, Michael L. Jones, Maureen C. Howard, Protective effects of IL-4 and IL-10 against immune complex-induced lung injury Journal of Immunology. ,vol. 151, pp. 5666- 5674 ,(1993)
Michael S. Mulligan, Peter A. Ward, Immune complex-induced lung and dermal vascular injury. Differing requirements for tumor necrosis factor-alpha and IL-1. Journal of Immunology. ,vol. 149, pp. 331- 339 ,(1992)
D.L. Scott, Etanercept in arthritis. International Journal of Clinical Practice. ,vol. 59, pp. 114- 118 ,(2005) , 10.1111/J.1742-1241.2005.00380.X
M S Mulligan, A R Rudolph, C G Yeh, P A Ward, Protective effects of soluble CR1 in complement- and neutrophil-mediated tissue injury. Journal of Immunology. ,vol. 148, pp. 1479- 1485 ,(1992)
Danielle G. Souza, Adriana C. Soares, Vanessa Pinho, Humberto Torloni, Luiz F.L. Reis, Mauro T. Martins, Adriana A.M. Dias, Increased Mortality and Inflammation in Tumor Necrosis Factor-Stimulated Gene-14 Transgenic Mice after Ischemia and Reperfusion Injury The American Journal of Pathology. ,vol. 160, pp. 1755- 1765 ,(2002) , 10.1016/S0002-9440(10)61122-4
Tiina Karu, Photobiology of low-power laser effects. Health Physics. ,vol. 56, pp. 691- 704 ,(1989) , 10.1097/00004032-198905000-00015