Coordinated gene expression by post-transcriptional regulons in African trypanosomes

作者: Marc Ouellette , Barbara Papadopoulou

DOI: 10.1186/JBIOL203

关键词:

摘要: The regulation of gene expression in trypanosomes is unique. In the absence transcriptional control at level initiation, a subset Trypanosoma brucei genes form post-transcriptional regulons which mRNAs are co-regulated response to differentiation signals. See research articles http://www.biomedcentral.com/1471-2164/10/427 , http://www.biomedcentral.com/1471-2164/10/482 and http://www.biomedcentral.com/1471-2164/10/495 .

参考文章(13)
P.J. Martínez-Calvillo, S., Yan, S., Nguyen, D., Fox, M., Stuart, K. y Myler, Transcription of Leishmania major Friedlin chromosome 1 initiates in both directions within a single region. Molecular Cell. ,vol. 11, pp. 1291- 1299 ,(2003) , 10.1016/S1097-2765(03)00143-6
Bryan C Jensen, Dhileep Sivam, Charles T Kifer, Peter J Myler, Marilyn Parsons, Widespread variation in transcript abundance within and across developmental stages of Trypanosoma brucei BMC Genomics. ,vol. 10, pp. 482- 482 ,(2009) , 10.1186/1471-2164-10-482
Simon Haile, Barbara Papadopoulou, Developmental regulation of gene expression in trypanosomatid parasitic protozoa. Current Opinion in Microbiology. ,vol. 10, pp. 569- 577 ,(2007) , 10.1016/J.MIB.2007.10.001
Sean Thomas, Amanda Green, Nancy R Sturm, David A Campbell, Peter J Myler, Histone acetylations mark origins of polycistronic transcription in Leishmania major BMC Genomics. ,vol. 10, pp. 152- 152 ,(2009) , 10.1186/1471-2164-10-152
Stuart K. Archer, Van-Duc Luu, Rafael A. de Queiroz, Stefanie Brems, Christine Clayton, Trypanosoma brucei PUF9 Regulates mRNAs for Proteins Involved in Replicative Processes over the Cell Cycle PLoS Pathogens. ,vol. 5, pp. e1000565- ,(2009) , 10.1371/JOURNAL.PPAT.1000565
Jack D. Keene, RNA regulons: coordination of post-transcriptional events Nature Reviews Genetics. ,vol. 8, pp. 533- 543 ,(2007) , 10.1038/NRG2111
Antonio M. Estévez, The RNA-binding protein TbDRBD3 regulates the stability of a specific subset of mRNAs in trypanosomes Nucleic Acids Research. ,vol. 36, pp. 4573- 4586 ,(2008) , 10.1093/NAR/GKN406
Rafael Queiroz, Corinna Benz, Kurt Fellenberg, Jörg D Hoheisel, Christine Clayton, Transcriptome analysis of differentiating trypanosomes reveals the existence of multiple post-transcriptional regulons BMC Genomics. ,vol. 10, pp. 495- 495 ,(2009) , 10.1186/1471-2164-10-495
Todd A Minning, D Brent Weatherly, James Atwood, Ron Orlando, Rick L Tarleton, The steady-state transcriptome of the four major life-cycle stages of Trypanosoma cruzi BMC Genomics. ,vol. 10, pp. 370- 370 ,(2009) , 10.1186/1471-2164-10-370