Influence of the cold challenge on the discriminatory capacity of the digital distal-dorsal difference in the thermographic assessment of Raynaud's phenomenon.

摘要: Abstract Objectives To investigate the influence of a standardised cold stress test (CST) on thermographic ‘distal–dorsal difference’ (DDD) and its capacity to differentiate between disease states in assessment Raynaud's phenomenon (RP), compare discriminatory DDD individual digits with composite indices multiple digits. Methods Thermographic images 55 patients primary RP (PRP, n = 27) systemic sclerosis (SSc, n = 28) who had undergone were retrospectively reviewed. The for digits, scores calculated at baseline (23 °C), 10 min following CST. mean DDD, proportion clinically meaningful Results There was more pronounced decrease (indicating reduced distal perfusion) CST PRP compared SSc. disparity response groups narrowed differences that present baseline, reducing all endpoints. Sparing thumbs occurs greater extent SSc (P  Conclusions is lost may not be essential RP, potentially allowing use thermography clinical practise.