Which Variable of Stenosis Severity Best Describes the Significance of an Isolated Left Anterior Descending Coronary Artery Lesion?: Correlation Between Quantitative Coronary Angiography, Intracoronary Doppler Measurements and High Dose Dipyridamole Echocardiography

摘要: Abstract Objectives. This study sought to investigate the angiographic or intracoronary Doppler variables of stenosis severity that best correlate with results dipyridamole echocardiography. Background. Quantitative coronary angiography and flow velocity assessments are commonly used techniques for objective identification significant artery stenosis. Methods. Thirty patients an isolated lesion left anterior descending (LAD) were studied by means on-line quantitative arteriography, measurements echocardiography 6 months after percutaneous transluminal angioplasty. The arteriographic analyses performed on-line; post-stenotic velocities measured at baseline adenosine infusion. Angiographic compared corresponding echocardiographic data analyzed discriminant analysis. Results. response was positive in 11 (37%). cutoff values predicting abnormal 1) stenotic reserve 2.8 (p = 0.0001); 2) 59% diameter 3) minimal lumen 1.35 mm 0.001); 4) 2.0 0.0002); 5) maximal peak 60 cm/s during hyperemia 0.04). Multivariate analysis identified as only independent predictor ischemia Conclusions. Stenotic is variable describes functional significance LAD lesion, a value response. Furthermore, relate test better than variables.