Adaptation of oral streptococci to low pH.

作者: Robert G. Quivey , Wendi L. Kuhnert , Kristina Hahn

DOI: 10.1016/S0065-2911(00)42004-7

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摘要: The strategies employed by oral streptococci to resist the inimical influences of acidification reflect diverse and dynamic niches human mouth. All are capable rapid degradation sugar acidic end-products. As a result, pH value their immediate environment can plummet levels where glycolysis growth cease. At this point, approaches for survival in acid separate organisms. Streptococcus mutans, example, relies on its F-ATPase, protect itself from pumping protons out cells. S. salivarius responds degrading urea ammonia sanguis produces arginolysis. mechanisms which these organisms regulate particular escape route now being explored experimentally. picture that emerges is acid-adaptive regulatory differ markedly those Gram-negative bacteria. What remains be elucidated breadth acid-response systems how they permit microbes sustain themselves face low bacterial competition present respective niches. In article, we summarize reports concerning means either utilize subdue competitors or until values return more favorable level.

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