COVID-19 and mutations a threat level assessment

摘要: A mutation is defined as an alteration in the DNA or RNA sequences of a genome which may consequently confer new phenotypic and genotypic advantage both increasing virulence well survival virus pathogen. At this current point time there are 4 known major variants original SARS-CoV-2 virus, namely English variant (B.1.1.7), South African (B.1.351), Brazilian (VOC202101/02 (P.1) VUI202101/01) similar to that found North America (B.1.526), all have varying levels resistance infectivity. It evident pose international health risk, mutations E484K N501Y two most implicated mutations. being concerning it aids immune evasion drastically causes efficacy vaccines be reduced by large margins. The worrisome B.1.351 harbors above upmost importance targeted synthesized ensure immunized individuals effective protection against these variants. Until specific offer little long-term protection, however do level immunity stop severe infections. thus advised vaccination programs should continue earnest degree conferred.