摘要: Most proteins within living organisms contain glycans. Glycan structures can modulate the biological properties and functions of glycoproteins. The major glycans glycoproteins be classified into two groups, N-glycans O-glycans, according to their glycan-peptide linkage regions. Developments in glycobiology have revealed a new type glycosidic peptide portion, O-mannosyl linkage, mammals, while so far it had been thought specific yeast. This review will give an outline mammalian Since one most well known O-mannosyl-modified is dystroglycan, functional aspects glycan dystroglycan described help understand this glycobiological field.