摘要: Les mycotoxines sont des metabolites secondaires fabriques par les moisissures et contaminant de nombreuses denrees alimentaires. productrices cancerogenes (Fusarium, Aspergillus Penicillium) se developpent soit au champ, lors du stockage. resistantes aux procedes transformation l’agroalimentaire. Lors d’ingestion ou d’inhalation, elles peuvent etre responsables a long terme developpement cancers. aflatoxines reconnues comme hepatocancerogenes, mais egalement l’origine cancer pulmonaire apres metabolisation en epoxyde d’adduit l’ADN. fumonisines provoquent cancers renaux hepatiques chez animaux sembleraient associees l’oesophage l’humain perturbant la synthese sphingolipides. L’ochratoxine A est voies urinaires superieures derives quinone reagissant avec Dans ce chapitre, nous donnerons un apercu etudes carcinogenicite l’animal, epidemiologiques existantes. Nous analyserons mecanismes moleculaires biomarqueurs.
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