HMG-CoA reductase inhibitors for treatment of hypercholesterolemia.

作者: John A. Oates , Alastair J.J. Wood , Scott M. Grundy

DOI: 10.1056/NEJM198807073190105

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摘要: THE recent introduction of a unique class of cholesterol-lowering drugs offers new promise for the treatment of hypercholesterolemia. These drugs are inhibitors of 3-hydroxy-3-…

参考文章(79)
SM Grundy, A Chait, JD Brunzell, None, Familial combined hyperlipidemia workshop Arteriosclerosis. ,vol. 7, pp. 203- 207 ,(1989) , 10.1007/978-3-642-83665-7_4
Joseph L. Goldstein, Michael S. Brown, The LDL receptor defect in familial hypercholesterolemia. Implications for pathogenesis and therapy. Medical Clinics of North America. ,vol. 66, pp. 335- 362 ,(1982) , 10.1016/S0025-7125(16)31424-9
K H Weisgraber, S C Rall, R W Mahley, Human E apoprotein heterogeneity. Cysteine-arginine interchanges in the amino acid sequence of the apo-E isoforms. Journal of Biological Chemistry. ,vol. 256, pp. 9077- 9083 ,(1981) , 10.1016/S0021-9258(19)52510-8
S M Grundy, Pathogenesis of hyperlipoproteinemia. Journal of Lipid Research. ,vol. 25, pp. 1611- 1618 ,(1984) , 10.1016/S0022-2275(20)34439-4
Akira Yamamoto, Hiroshi Sudo, Akira Endo, Therapeutic effects of ML-236B in primary hypercholesterolemia Atherosclerosis. ,vol. 35, pp. 259- 266 ,(1980) , 10.1016/0021-9150(80)90124-0
Donald B. Hunninghake, Lovastatin: Follow-up Ophthalmologic Data JAMA: The Journal of the American Medical Association. ,vol. 259, pp. 354- 355 ,(1988) , 10.1001/JAMA.1988.03720030022020
P. T. Ma, G. Gil, T. C. Sudhof, D. W. Bilheimer, J. L. Goldstein, M. S. Brown, Mevinolin, an inhibitor of cholesterol synthesis, induces mRNA for low density lipoprotein receptor in livers of hamsters and rabbits Proceedings of the National Academy of Sciences of the United States of America. ,vol. 83, pp. 8370- 8374 ,(1986) , 10.1073/PNAS.83.21.8370
D. K. Spady, D. W. Bilheimer, J. M. Dietschy, Rates of receptor-dependent and -independent low density lipoprotein uptake in the hamster. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 80, pp. 3499- 3503 ,(1983) , 10.1073/PNAS.80.11.3499
Robert I Levy, John F Brensike, Stephen E Epstein, Sheryl F Kelsey, Eugene R Passamani, John M Richardson, Irving K Loh, Neil J Stone, Robert F Aldrich, James W Battaglini, The influence of changes in lipid values induced by cholestyramine and diet on progression of coronary artery disease: results of NHLBI Type II Coronary Intervention Study. Circulation. ,vol. 69, pp. 325- 337 ,(1984) , 10.1161/01.CIR.69.2.325