摘要: An American advertisement for engine oil filters says, “You can pay me now or you later!” This challenge might do equally well directly observed therapy tuberculosis. With the filter, buyers are weighing cost of routine preventive filtering against eventually overhauling because lack maintenance. tuberculosis, balance is between costs monitoring to ensure that treatment completed versus enormous expense poor adherence, failure, recurrent hospitalisation, drug resistance, and continuing transmission infection. Directly refers process whereby a health care worker trained lay person watches while patient swallows anti-tuberculous drugs over six nine months treatment. The be administered in daily intermittent (two three times week) regimens wide range clinical settings at home, work, school, any convenient designated area.1 Directly tuberculosis has its origins late 1940s early 1950s, when British researchers used it trials chemotherapy Africa, Asia, London.2 In United States, despite arguments Sbarbaro others all patients should receive supervised therapy,2 self administration was standard practice except predicted …