Sequence preferences in the binding to DNA of triostin A and TANDEM as reported by DNase I footprinting

作者: C.M.Loretta Low , Richard K. Olsei , Michael J. Waring

DOI: 10.1016/0014-5793(84)81209-0

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摘要: Six or seven triostin-binding sites have been identified in a 160-base-pair DNA restriction fragment containing the tyr T promoter sequence. Each is centred round CpG step, and minimum binding site-size appears to be six base pairs. The are practically same as those reported for echinomycin by DNase I digestion. Only two protected of TANDEM, des-N-tetramethyl analogue triostin A; they around sequences ATA TAT.

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