Norovirus and sapovirus antigens
作者： Colin McCoin , Michael Vajdy , Michael Houghton , Doris Coit , Angelica Medina-Selby
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摘要: Immunogenic compositions that elicit immune responses against Norovirus and Sapovirus antigens are described. In particular, the invention relates to polynucleotides encoding one or more capsid proteins other immunogenic viral polypeptides from strains of and/or Sapovirus, coexpression such with adjuvants, methods using in applications including immunization production viral-like particles (VLPs). Methods for producing Norovirus- Sapovirus-derived multiple epitope fusion polyproteins comprising polypeptides, polynucleotides, VLPs, adjuvants also The may contain than antigens, can be used pathogens cause diarrheal diseases, as derived rotavirus.
google.com.tr参考文章(48)
Judith M. Ball, M. K. Estes, M. E. Hardy, M. E. Conner, A. R. Opekun, D. Y. Graham, Recombinant Norwalk virus-like particles as an oral vaccine Archives of virology. Supplementum. ,vol. 12, pp. 243- 249 ,(1996) , 10.1007/978-3-7091-6553-9_26
Sergio Pichuantes, Hepatitis a virus nucleotide sequences, recombinant proteins and uses thereof ,(2002)
Jill Catherine Makin, Andrew David Bacon, Influenza vaccine composition with chitosan adjuvant ,(2000)
Frank R. Masiarz, Denis J. Gospodarowicz, Truncated keratinocyte growth factor (KGF) having increased biological activity ,(1994)
Koen Hellendoorn, Charles J. Arntzen, Xiuren Zhang, William D. O. Hamilton, Dwayne D. Kirk, Timothy D. Jones, Hugh S. Mason, Vectors and methods for immunization against Norwalk virus using transgenic plants ,(2004)
Mary K. Estes, David Y. Graham, Xi Jiang, Methods and reagents to detect and characterize norwalk and related viruses Official Gazette of the United States Patent and Trademark Office Patents. ,(1990)
X. Jiang, W. D. Cubitt, T. Berke, W. Zhong, X. Dai, S. Nakata, L. K. Pickering, D. O. Matson, Sapporo-like human caliciviruses are genetically and antigenically diverse Archives of Virology. ,vol. 142, pp. 1813- 1827 ,(1997) , 10.1007/S007050050199
Rebecca L. Fankhauser, Jacqueline S. Noel, Stephan S. Monroe, Tamie Ando, Roger I. Glass, Molecular Epidemiology of “Norwalk-like Viruses” in Outbreaks of Gastroenteritis in the United States The Journal of Infectious Diseases. ,vol. 178, pp. 1571- 1578 ,(1998) , 10.1086/314525
Anne M. Hutson, Robert L. Atmar, Donald M. Marcus, Mary K. Estes, Norwalk Virus-Like Particle Hemagglutination by Binding to H Histo-Blood Group Antigens Journal of Virology. ,vol. 77, pp. 405- 415 ,(2003) , 10.1128/JVI.77.1.405-415.2003
Ee Ling Seah, John A. Marshall, Peter J. Wright, trans Activity of the Norovirus Camberwell Proteinase and Cleavage of the N-Terminal Protein Encoded by ORF1 Journal of Virology. ,vol. 77, pp. 7150- 7155 ,(2003) , 10.1128/JVI.77.12.7150-7155.2003