Bicyclo[3,1,0]hexane containing oxazolidinone antibiotic and derivatives thereof
作者： Yasumichi Fukuda , Milton L. Hammond
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摘要: Oxazolidinones having a bicyclic[3.1.0]hexane containing moiety, which are effective against aerobic and anerobic pathogens such as multi-resistant staphylococci, Streptococci enterococci, Bacteroides spp., Clostridia spp.species, well acid-fast organisms MYCOBACTERIUM TUBERCULOSISand other mycobacterial species. The compounds represented by structural formula I: its enantiomer, diastereomer, or pharmaceutically acceptable salt ester thereof, wherein the variables R1, R2, R3, R4a, A, Ar, HAr, n, r, s defined herein.
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