Photochemical addition of cyclic ethers/acetals to olefins using tBuOOtBu: Synthesis of masked ketones/aldehydes and diols
作者： Mamiko Hayakawa , Rina Shimizu , Hajime Omori , Hisashi Shirota , Kou Uchida
DOI: 10.1016/J.TET.2020.131557
关键词:
摘要: Abstract A fast photochemical C–C bond formation between cyclic ethers/acetals and olefins using di-tert-butyl peroxide (DTBP) was developed. This method provides easy access to 2-substituted ethers, 2- or 4-substituted acetals. Acyl/formyl groups diols can be obtained by the hydrolysis of acetals, respectively. The reactions proceeded at room temperature gave expected products in good excellent yields; efficient were completed within 0.5 h at >95% yield.
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