The PI3K/AKT cell signaling pathway is involved in regulation of osteoporosis.

作者: Yi-Bing Bai , Yuan-Zheng Ma , Jian-Cheng Xi , Hai-Yu Zang , Li-Xin Guo

DOI: 10.3109/10799893.2015.1041647

关键词:

摘要: … Polyclonal antibodies against phospho-PI3K, phospho-Akt, and phospho-PDK1 used in this study were purchased from Cell Signaling Technology, Berkeley, CA. Band density was …

参考文章(34)
Alex Toker, Alexandra C Newton, Cellular Signaling: Pivoting around PDK-1 Cell. ,vol. 103, pp. 185- 188 ,(2000) , 10.1016/S0092-8674(00)00110-0
Songlin Peng, Guangqian Zhou, Keith DK Luk, Kenneth MC Cheung, Zhaoyang Li, Wing Moon Lam, Zhongjun Zhou, William W Lu, None, Strontium promotes osteogenic differentiation of mesenchymal stem cells through the Ras/MAPK signaling pathway Cellular Physiology and Biochemistry. ,vol. 23, pp. 165- 174 ,(2009) , 10.1159/000204105
Lynn Huyck, Christophe Ampe, Marleen Van Troys, The XTT Cell Proliferation Assay Applied to Cell Layers Embedded in Three-Dimensional Matrix Assay and Drug Development Technologies. ,vol. 10, pp. 382- 392 ,(2012) , 10.1089/ADT.2011.391
Veronica Ulici, Katie D. Hoenselaar, Hanga Agoston, David D. McErlain, Joseph Umoh, Subrata Chakrabarti, David W. Holdsworth, Frank Beier, The role of Akt1 in terminal stages of endochondral bone formation: Angiogenesis and ossification Bone. ,vol. 45, pp. 1133- 1145 ,(2009) , 10.1016/J.BONE.2009.08.003
Gunilla Westergren-Thorsson, Per-Ola Önnervik, Lars-ÅKe Fransson, Anders Malmström, Proliferation of cultured fibroblasts is inhibited by L-iduronate-containing glycosaminoglycans. Journal of Cellular Physiology. ,vol. 147, pp. 523- 530 ,(1991) , 10.1002/JCP.1041470319
Tetsuro Enomoto, Yuriko Furuya, Yoshiya Tomimori, Kaoru Mori, Jun-ichi Miyazaki, Hisataka Yasuda, Establishment of a new murine model of hypercalcemia with anorexia by overexpression of soluble receptor activator of NF-κB ligand using an adenovirus vector Journal of Bone and Mineral Metabolism. ,vol. 29, pp. 414- 421 ,(2011) , 10.1007/S00774-010-0235-7
William D. Leslie, Suzanne N. Morin, Osteoporosis epidemiology 2013: implications for diagnosis, risk assessment, and treatment. Current Opinion in Rheumatology. ,vol. 26, pp. 440- 446 ,(2014) , 10.1097/BOR.0000000000000064
Hiroshi Sakaue, Wataru Ogawa, Michihiro Matsumoto, Shoji Kuroda, Masafumi Takata, Tadanori Sugimoto, Bruce M. Spiegelman, Masato Kasuga, Posttranscriptional Control of Adipocyte Differentiation through Activation of Phosphoinositide 3-Kinase Journal of Biological Chemistry. ,vol. 273, pp. 28945- 28952 ,(1998) , 10.1074/JBC.273.44.28945
Kyung Mi Son, Hee Chul Park, Na Ryoung Kim, In-Seop Lee, Hyeong-Cheol Yang, Enhancement of the ALP activity of C3H10T1/2 cells by the combination of an oxysterol and apatite Biomedical Materials. ,vol. 5, pp. 044107- 044107 ,(2010) , 10.1088/1748-6041/5/4/044107