EVOLUTION OF BIOACTIVE SEQUENCE-DEFINED SYNTHETIC POLYMERS USING DNA-TEMPLATED POLYMERIZATION
作者： Lichtor Phillip Andrew , Liu David R , Chen Zhen
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摘要: The present invention provides methods and compositions for performing ordered multi- step syntheses involving modified nucleic acids by acid-mediated chemistry. This approach is useful generating sequence-defined highly functionalized acid polymers. also polymers that bind to proteins of interest (e.g., PCSK9 IL-6), which are implicated in human disease.
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