Luminescent nanocarriers for simultaneous drug or gene delivery and imaging tracking
作者： Xilin Bai , Shiguo Wang , Suying Xu , Leyu Wang
DOI: 10.1016/J.TRAC.2015.04.027
关键词:
摘要: Drug or gene delivery based on nanostructure is promising for treatments of cancers to solve a variety issues associated with traditional therapeutic agents from poor bioavailability systemic toxicity. For real-time monitoring the process, imaging-guided therapy has attracted growing interest in biomedical applications. Luminescent nanostructures serve as an essential tool illuminating pathway drug systems. Considering their crucial role medical applications, we summarize recent progress luminescent drug- gene-delivery nanocarriers simultaneous imaging tracking. We also discuss design principles and critical faced by multifunctional engineering, which might provide guidance further development this field.
elsevier.com
sci-hub.se 参考文章(70)
Sheng Huang, Shan Peng, Yuanbao Li, Jiabin Cui, Hongli Chen, Leyu Wang, Development of NIR-II fluorescence image-guided and pH-responsive nanocapsules for cocktail drug delivery Nano Research. ,vol. 8, pp. 1932- 1943 ,(2015) , 10.1007/S12274-015-0702-5
Xilin Bai, Suying Xu, Jiali Liu, Leyu Wang, Upconversion luminescence tracking of gene delivery via multifunctional nanocapsules Talanta. ,vol. 150, pp. 118- 124 ,(2016) , 10.1016/J.TALANTA.2015.08.038
Qian He, Sheng Huang, Suying Xu, Leyu Wang, pH-responsive cocktail drug nanocarriers by encapsulating paclitaxel with doxorubicin modified poly(amino acid) RSC Advances. ,vol. 5, pp. 43148- 43154 ,(2015) , 10.1039/C5RA05939A
Ruichan Lv, Shili Gai, Yunlu Dai, Fei He, Na Niu, Piaoping Yang, Surfactant-free synthesis, luminescent properties, and drug-release properties of LaF3 and LaCO3F hollow microspheres. Inorganic Chemistry. ,vol. 53, pp. 998- 1008 ,(2014) , 10.1021/IC402468K
Peng Zhao, Yihua Zhu, Xiaoling Yang, Jianhua Shen, Xin Jiang, Jie Zong, Chunzhong Li, Multifunctional MnO2 nanosheet-modified Fe3O4@SiO2/NaYF4:Yb, Er nanocomposites as novel drug carriers Dalton Transactions. ,vol. 43, pp. 451- 457 ,(2014) , 10.1039/C3DT52066H
Huan Xu, Liang Cheng, Chao Wang, Xinxing Ma, Yonggang Li, Zhuang Liu, Polymer encapsulated upconversion nanoparticle/iron oxide nanocomposites for multimodal imaging and magnetic targeted drug delivery Biomaterials. ,vol. 32, pp. 9364- 9373 ,(2011) , 10.1016/J.BIOMATERIALS.2011.08.053
Li Shang, Shaojun Dong, G. Ulrich Nienhaus, Ultra-small fluorescent metal nanoclusters: Synthesis and biological applications Nano Today. ,vol. 6, pp. 401- 418 ,(2011) , 10.1016/J.NANTOD.2011.06.004
Changjun Liu, Peng Zhang, Xinyun Zhai, Feng Tian, Wenchen Li, Jianhai Yang, Yuan Liu, Hongbo Wang, Wei Wang, Wenguang Liu, Nano-carrier for gene delivery and bioimaging based on carbon dots with PEI-passivation enhanced fluorescence. Biomaterials. ,vol. 33, pp. 3604- 3613 ,(2012) , 10.1016/J.BIOMATERIALS.2012.01.052
Ping'an Ma, Haihua Xiao, Xiaoxue Li, Chunxia Li, Yunlu Dai, Ziyong Cheng, Xiabin Jing, Jun Lin, None, Rational Design of Multifunctional Upconversion Nanocrystals/Polymer Nanocomposites for Cisplatin (IV) Delivery and Biomedical Imaging Advanced Materials. ,vol. 25, pp. 4898- 4905 ,(2013) , 10.1002/ADMA.201301713
Suying Xu, Sheng Huang, Qian He, Leyu Wang, Upconversion nanophosphores for bioimaging Trends in Analytical Chemistry. ,vol. 66, pp. 72- 79 ,(2015) , 10.1016/J.TRAC.2014.11.014