Prevalence and distribution of cervical high-risk human papillomavirus and cytological abnormalities in women living with HIV in Denmark – the SHADE

摘要: Women living with HIV (WLWH) are at increased risk of persistent human papillomavirus (HPV) infection, cervical dysplasia and cancer compared women from the general population (WGP). We assessed prevalence distribution high-risk (hr) HPV infection cytological abnormalities in WLWH WGP Denmark. Predictors were estimated WLWH. consecutively enrolled Study on HIV, Abnormalities infections Denmark (SHADE) 2011 examined for abnormalities. matched age prior findings an earlier study. demographics retrieved nationwide Danish Cohort Study. Logistic regression was used to estimate predictors hrHPV Of 334 included 26.4 % positive as opposed 16.6 % (p  1 h genotype present) (38.5 % versus 25.7 %, p = 0.030). Hr genotypes descending order frequency HPV58 (7.1 %), 52 (5.4 %), 16 (4.8 %) HPV16 (4.1 %), (2.8 %) 58 (2.4 %) WGP. short duration HAART (adjusted OR per year 0.90 (95 % CI 0.84-0.96)), AIDS inclusion 3.61 1.75-7.46)), ≥5 lifetime sexual partners 2.20 1.08-4.49)), debut <16 years 2.05 1.03-4.10)) CD4 < 350 cells/μL 2.53 1.20-5.40)). Cytological prevalent 10.4 % vs. 5.2 % (p = 0.0003) In hrHPV, predicted 0.83 0.71-0.97)). presented more abnormalities, a different Cervical by HAART.