The RNAi Universe in Fungi: A Varied Landscape of Small RNAs and Biological Functions

作者: Santiago Torres-Martínez , Rosa M. Ruiz-Vázquez

DOI: 10.1146/ANNUREV-MICRO-090816-093352

关键词:

摘要: RNA interference (RNAi) is a conserved eukaryotic mechanism that uses small molecules to suppress gene expression through sequence-specific messenger degradation, translational repression, or transcriptional inhibition. In filamentous fungi, the protective function of RNAi in maintenance genome integrity well known. However, knowledge regulatory role fungi has had wait until recent identification different endogenous classes, which are generated by distinct pathways. addition, research on new fungal models uncovered RNAs and pathways regulation diverse biological functions. this review, we give an up-to-date overview classes their roles defense physiology development, as interaction with biotic abiotic environments.

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