Chemotherapy Intensity and Long-Term Outcome in AML

摘要: Treatment alternatives and long-term results in adult AML were recently reported from six multicenter randomized studies (Table 1). Cytarabine (AraC) 200versus 100mg/m2/d, standard induction maintenance courses was administered 326 patients. The complete remission (CR) rate 64% 58%, respectively (n.s.). Median disease-free survival (DFS) 10 months 5 year DFS 10% both arms [1]. In a study on different intensity of postconsolidation treatment, patients received four dose consolidation after then to stop treatment or receive either lower intensive sequential maintenance. 448 age ≼ 55 years, the CR is 68%. 13 24%, similar three groups [2]. Intensive compared with prolonged allogeneic BMT first CR.