Lead induced Oxidative Stress Mediated Myocardial Injury: A Review

摘要: Lead is a naturally occurring toxic element. It has several industrial uses and highly for living organisms if it enters accumulates in body. Long term exposure to this heavy metal either environmentally or occupationally may cause various types of ailments among which myocardial injury hepato-toxicity are worth mentioning. induced occurs primarily through lead mediated oxidative damage tissue. stimulates generation reactive oxygen species (ROS) causes biochemical, cytological physiological detrimental alterations the cardiac Administration supplementation antioxidant rich aqueous curry leaves (a popular spice herb, Murraya koenigii) extract melatonin, natural indole, separately have potentiality provide protection against damage. Their combination can stronger brought about following almost complete. Thus, we think designing potent drug formulation with very low no toxicity stress using melatonin future therapeutic relevance.