Retinoic acid receptors: transcription factors modulating gene regulation, development, and differentiation.
作者： Elwood Linney
DOI: 10.1016/S0070-2153(08)60538-4
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摘要: Publisher Summary This chapter discusses the relatively new field of retinoic acid receptors (RARs) with that biological effects retinoids and suggests roles for these strategies experimentally examining RAR function specificity. The RARs are members a superfamily ligand-inducible transcription factors includes steroid receptors, thyroid hormone vitamin D3 receptor. remain very attractive set candidate genes may play pivotal in differentiation, development, gene regulation. describes modular structure molecular specificity receptor-like retinoid X as well current future approaches dissecting developmental receptors.
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