Feeding and communication impairments in infants with central grey matter lesions following perinatal hypoxic–ischaemic injury

摘要: Abstract Background Basal ganglia and thalamic (BGT) injury is common after acute perinatal hypoxia–ischaemia. Cerebral palsy the most obvious consequence of BGT affecting 70–75% survivors predictable from neonatal magnetic resonance imaging (MRI). However there no equivalent predictive data for other specific outcomes. Feeding communication impairments are also in children following hypoxic–ischaemic encephalopathy (HIE) injury. Aims To describe, infants with HIE injury, prevalence feeding impairments; to evaluate accuracy early MRI predicting these Methods 175 term were studied. Brain lesions classified by site severity scans. Motor, documented at 2 years. Results occurred 65% 82% 126 respectively related strongly motor impairment. Forty-one had a gastrostomy or long-term nasogastric tube. Injury all brain regions was significantly associated impairment on univariate analysis. On logistic regression analysis (OR 10.9) mesencephalic 3.7) independently impairment; 10.5) pontine 3.8) gastrostomy; 20.1) Conclusions very brainstem origin can be well predicted