Metal mesh scaffold for tissue engineering of membranes.

摘要: Engineering of the membrane-like tissue structures to be utilized in highly dynamic loading environments such as cardiovascular system has been a challenge past decade. Scaffolds are critical components engineered membranes and allow them being formed vitro remain secure vivo when implanted body. Several approaches have taken develop scaffolds for membranes. However, all methods entail limitations due structural vulnerability, short-term functionality, mechanical properties resulted membrane constructs. To overcome these issues, we developed novel hybrid scaffold made an extra thin layer metal mesh tightly enclosed by biological matrix components. This approach retains advantages using while developing strong extracellular that can stand various types loads after implantation inside