Clinical manifestations in the West Nile virus outbreak.

摘要: During the summer of 1996 an unusual clustering meningoencephalitis cases was recorded in Capital City, Bucharest, and some areas from South-East Romania. After initial suspicion enteroviral etiology discarded, West Nile confirmed by specific antibodies demonstration through hemagglutination-inhibition ELISA tests. This study included 251 patients with diagnoses acute encephalitis (166 cases), meningitis (57 cases) febrile disease (33 cases). The patients' age ranged 1 to 89 years (mean 51.1 years). most frequent clinical manifestations were: fever (95.7% cephalalgia (92.6%), stiffness neck (89.1%), vomiting (62.5%), marked asthenia (46.5%), myalgia (28.9%). In addition, exhibited: alteration consciousness (89.2% tremor extremities (40.4%), ataxia (44%), paralysis (15.1%). fatality rate 15.1% encephalitis, 1.8% 0% disease.