The complete primary structure of a proline-rich phosphoprotein from human saliva.
作者： R.S. Wong , T. Hofmann , A. Bennick
DOI: 10.1016/S0021-9258(17)30083-2
关键词:
摘要: The complete amino acid sequence of a calcium-binding "proline-rich phosphoprotein," named Protein A, from human saliva was determined by automated and manual Edman degradation peptides obtained enzymatic chemical cleavage the intact protein. NH2-terminal pyrrolidone carboxylic identified means NMR. protein consists 106 acids, including 24 residues proline. 32 contain 13 15 negatively charged 2 phosphoserines, but only 1 In spite high concentration proline in COOH-terminal part molecule, longest oligoproline is tetraproline. contains number repeated sequences there are also several 3 or 4 identical with known collagen, characteristic occurrence glycine every third position collagen not found salivary A.
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