The mouse olfactory peduncle

摘要: The olfactory peduncle, the region connecting bulb with basal forebrain, contains several neural areas that have received relatively little attention. present work includes studies provide an overview of in mouse. An analysis cell soma size pars principalis (pP) anterior nucleus (AON) revealed considerable differences tissue organization between mice and rats. unbiased stereological study neuron number cell-dense regions externa (pE) pP AON 3-, 12-, 24-month-old indicated pE has about 16,500 cells 0.043 mm(3) 58,300 0.307 . Quantitative Golgi pyramidal neurons suggested mouse are similar to although smaller than those rat. immunohistochemical demonstrated all peduncular (pE, pP, dorsal cortex, ventral tenia tecta, tubercle piriform cortex) express either calbindin, calretinin, parvalbumin, somatostatin, vasoactive intestinal polypeptide, neuropeptide Y, or cholecystokinin (antigens commonly co-expressed by subspecies γ-aminobutyric acid [GABA]ergic neurons), relative numbers each type differ zones. Finally, electron microscopic comparison myelinated fibers lateral tract posterior peduncle is less orderly results a caveat for investigators who generalize data species, as both similarities laboratory rat were observed.