Potential of electrical discharge treatment to enhance the in vitro cytocompatibility and tribological performance of Co–Cr implant
作者： Amit Mahajan , Sarabjeet Singh Sidhu
DOI: 10.1557/JMR.2019.240
关键词:
摘要: In the current research, application and capability of electric discharge treatment (EDT) for enhancing cytocompatibility tribological properties medical-grade Co–Cr alloy were investigated. The specimens treated by copper tungsten (Cu–W) electrode in a deionized water tank (dielectric medium) at different spark energy levels. To examine substrates, MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] assay was performed to evaluate substrate cell viability. Furthermore, wear rate coefficient friction substrates examined on pin-on-disc tribometer. vitro results revealed that % viability MG-63 cells EDT sample approximately two times improved compared with untreated surface. showed samples have better reducing four higher resistance unmachined samples. surface modification 10 A 60 µs pulse on-time 150 off-time found as significant parameters both assessments.
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sci-hub.se 参考文章(35)
K Ikeuchi, J Kusaka, Y Morita, H Yoshida, Effect of tribochemical reaction on wear of silicon carbide for joint prostheses KOREAN ASSOC CRYSTAL GROWTH, INC. ,(2001)
Akihiko Chiba, Kazushige Kumagai, Naoyuki Nomura, Satoru Miyakawa, Pin-on-disk wear behavior in a like-on-like configuration in a biological environment of high carbon cast and low carbon forged Co–29Cr–6Mo alloys Acta Materialia. ,vol. 55, pp. 1309- 1318 ,(2007) , 10.1016/J.ACTAMAT.2006.10.005
Vandana Srivastava, Arvind Singh Negi, J.K. Kumar, M.M. Gupta, Suman P.S. Khanuja, Plant-based anticancer molecules: a chemical and biological profile of some important leads. Bioorganic & Medicinal Chemistry. ,vol. 13, pp. 5892- 5908 ,(2005) , 10.1016/J.BMC.2005.05.066
J.A. Ortega-Saenz, M.A.L. Hernandez-Rodriguez, V. Ventura-Sobrevilla, R. Michalczewski, J. Smolik, M. Szczerek, Tribological and corrosion testing of surface engineered surgical grade CoCrMo alloy Wear. ,vol. 271, pp. 2125- 2131 ,(2011) , 10.1016/J.WEAR.2010.12.062
Mitsuo Niinomi, Recent metallic materials for biomedical applications Metallurgical and Materials Transactions A-physical Metallurgy and Materials Science. ,vol. 33, pp. 477- 486 ,(2002) , 10.1007/S11661-002-0109-2
Karin S. Straley, Cheryl Wong Po Foo, Sarah C. Heilshorn, Biomaterial Design Strategies for the Treatment of Spinal Cord Injuries Journal of Neurotrauma. ,vol. 27, pp. 1- 19 ,(2010) , 10.1089/NEU.2009.0948
James Hesketh, Michael Ward, Duncan Dowson, Anne Neville, The composition of tribofilms produced on metal-on-metal hip bearings Biomaterials. ,vol. 35, pp. 2113- 2119 ,(2014) , 10.1016/J.BIOMATERIALS.2013.11.065
P Wu, C.Z Zhou, X.N Tang, Microstructural characterization and wear behavior of laser cladded nickel-based and tungsten carbide composite coatings Surface & Coatings Technology. ,vol. 166, pp. 84- 88 ,(2003) , 10.1016/S0257-8972(02)00730-2
B.D. Beake, T.W. Liskiewicz, Comparison of nano-f`retting and nano-scratch tests on biomedical materials Tribology International. ,vol. 63, pp. 123- 131 ,(2013) , 10.1016/J.TRIBOINT.2012.08.007
M. Alvarez-Vera, A. Juarez-Hernandez, C.E. Gonzalez-Rivera, R.D. Mercado-Solis, M.A.L. Hernandez-Rodriguez, Biotribological response of CoCr alloy with added boron under ball-on-disc tests Wear. ,vol. 301, pp. 243- 249 ,(2013) , 10.1016/J.WEAR.2012.11.074